Putrescine Oxidase Biocatalyst System Engineered with a Steel

gnrlbiotech

Neuroprotective Results of Casein-Derived Peptide Met-Lys-Professional (MKP) in a Hypertensive Mannequin

We’ve beforehand reported that casein hydrolysate, CH-3, from bovine milk and casein-derived tripeptide Met-Lys-Professional (MKP) has ACE inhibitory exercise and reduces blood strain. On this research, we investigated the therapeutic results of MKP in a hypertensive rat mannequin (7-week-old male SHRSP/Izm rats). For long run analysis, rats have been fed both a weight loss program containing CH-Three or regular weight loss program.

 The survival price of SHRSP rats was considerably improved by consumption of CH-Three for 181 days. For brief time period analysis, rats have been orally administered artificial tripeptide MKP or distilled water for four weeks. MRI research demonstrated that hemorrhagic lesions have been noticed in two of 5 rats within the management group, whereas no hemorrhagic lesions have been noticed within the MKP group.

Volumetric evaluation utilizing MRI revealed that MKP administration inhibited atrophy of diencephalic areas. Histological examinations revealed that hemorrhage areas and astrogliosis within the hippocampus and cerebral cortex have been decrease within the MKP group than within the management group. Gene expression evaluation indicated that MKP administration diminished expression of genes associated to cerebral circulation insufficiency corresponding to immune responses (Cd74 and Prkcd), response to hypoxia (Ddit4Apold1, and Prkcd), reactive oxygen species metabolic course of (Ddit4 and Pdk4), and apoptotic course of (Ddit4Prkcd, and Sgk1), suggesting that MKP administration prevented cerebral ischemia related to hypertension.

 As well as, some genes encoding responses to hormone stimulus (FosDusp1, and Sik1) have been additionally downregulated. Serum aldosterone and corticosterone ranges have been additionally considerably decreased following MKP administration. The current research signifies that MKP reveals neuroprotective results in SHRSP rats by regulating cerebral circulation insufficiency and corticoid ranges. MKP administration could due to this fact be a possible therapeutic technique for hypertensive mind ailments corresponding to cerebrovascular illness.

gnrlbiotech
gnrlbiotech

Peptide Lv (Human)

008-71 100 μg
EUR 405

Peptide YY (PYY) (Human)

059-01 200 μg
EUR 119.88

Peptide YY (PYY) (3-36) (Human) - Antibody

H-059-02 100 μl
EUR 604.8

PLGF Immunizing Peptide

MBS426290-01mg 0.1mg
EUR 225

Galanin-Like Peptide (GALP) (Human) - Antibody

H-026-51 50 μl
EUR 604.8

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - Antibody

H-064-07 50 μl
EUR 238.68

GnRH Associated Peptide (GAP) (1-13) / GnRH Precursor Peptide (14-26) (Human)

029-03 500 μg
EUR 114.48

GnRH Associated Peptide (GAP) (1-24) / GnRH Precursor Peptide (14-37) (Human)

029-04 100 μg
EUR 114.48

GnRH Associated Peptide (GAP) (1-53) / GnRH Precursor Peptide (14-66) (Human)

029-05 20 μg
EUR 267.84

GnRH Associated Peptide (GAP) (25-53) / GnRH Precursor Peptide (38-66) (Human)

029-06 100 μg
EUR 114.48

Peptide YY (PYY) (3-36)-Gly (Human) - Antibody

H-059-08 100 μl
EUR 469.8

[Cys0]-Peptide YY (PYY) (3-19) (Human) - Antibody

H-059-16 100 μl
EUR 469.8

Gastrin Releasing Peptide (GRP) (Human) - Antibody

H-027-07 50 μl
EUR 238.68

[Cys20]-Peptide YY (PYY) (3-19) (Human) - Antibody

H-059-17 100 μl
EUR 469.8

Peptide YY (PYY) (Human) - Purified IgG Antibody

G-059-01 400 μg
EUR 438.48

Peptide-Depleted Plasma (Human)

MB-099-01 2 ml
EUR 119.88

Stresscopin Related Peptide (SRP) (Human) - Antibody

H-019-27 50 μl
EUR 604.8

Peptide YY (PYY) (3-36) (Human)

059-02 200 μg
EUR 102.6

C28 optimized peptide 6 (Human)

073-82 100 μg
EUR 235.44

Anti-Inflammatory Peptide 1

004-01 200 μg
EUR 27

Anti-Inflammatory Peptide 2

004-02 200 μg
EUR 27

Anti-Inflammatory Peptide 3

004-03 200 μg
EUR 27

Peptide YY (PYY) (Human) - EIA Kit

EK-059-01 96 wells
EUR 617.76

Peptide YY (PYY) (Human) - RIA Kit

RK-059-01 125 tubes
EUR 814.32

Galanin-Like Peptide (GALP) (36-60) (Human) - Antibody

H-026-55 50 μl
EUR 604.8

Galanin-Like Peptide (GALP) (Human)

026-51 100 μg
EUR 230.04

PACAP-Related Peptide (PRP) (Human)

052-10 200 μg
EUR 86.4

Anti-Angiogenic Peptide Library

L-008A 88 peptides
EUR 6067.44

T3 Peptide / Tumstatin (69-88) (Human)

016-50 100 μg
EUR 255.96

T7 Peptide / Tumstatin (74-98) (Human)

016-51 100 μg
EUR 255.96

Prolactin-Releasing Peptide-31 (PrRP-31) (Human) - Antibody

H-008-50 50 μl
EUR 604.8

Peptide YY (PYY) (3-36) (Human) - Purified IgG Antibody

G-059-02 200 μg
EUR 604.8

Gastrin Releasing Peptide (GRP) (Human)

027-07 200 μg
EUR 119.88

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - Purified IgG Antibody

G-064-07 400 μg
EUR 438.48

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human)

064-07 200 μg
EUR 114.48

Peptide YY (PYY) (1-36)-Gly (Human)

059-07 100 μg
EUR 295.92

Peptide YY (PYY) (3-36)-Gly (Human)

059-08 100 μg
EUR 282.96

Peptide YY (PYY) (2-36)-Gly (Human)

059-11 100 μg
EUR 267.84

Peptide YY (PYY) (4-36)-Gly (Human)

059-12 100 μg
EUR 267.84

Stresscopin Related Peptide (SRP) (Human)

019-27 100 μg
EUR 214.92

SHAAG Peptide / Chemokine (46-63) (Human)

072-32 100 μg
EUR 160.92

RFamide-Related Peptide 3 (RFRP-3) (Human) - Antibody

H-048-46 100 μl
EUR 604.8

Defensin I / Human Neutrophil Peptide-1 (HNP-1) (Human)

072-17 100 μg
EUR 370.44

Fractalkine Chemokine Domain peptide (41-52) (Human)

026-82 200 μg
EUR 160.92

Fractalkine Chemokine Domain peptide (53-60) (Human)

026-83 200 μg
EUR 135

Fractalkine Chemokine Domain peptide (60-71) (Human)

026-84 200 μg
EUR 160.92

Urotensin II Related Peptide (Human, Rat, Mouse) - Antibody

H-071-17 50 μl
EUR 604.8

Osteoblast Activating Peptide (OBAP) (Human)

055-52 100 μg
EUR 199.8

Human Proteome Signature Peptide Library

L-010 98 peptides
EUR 7804.08

C28 optimized peptide 15 Dimer (Human)

073-86 100 μg
EUR 420.12

Nesfatin-1-Like Peptide (NLP) (Human)

009-83 100 μg
EUR 469.8

APP 17mer peptide / APP770 (204-220) (Human)

018-74 100 μg
EUR 135

Galanin-Like Peptide (GALP) (Human) - Purified IgG Antibody

G-026-51 200 μg
EUR 604.8

C28 optimized peptide 15 Monomer (Human)

073-84 100 μg
EUR 258.12

Peptide YY (PYY) (3-36) (Human) - EIA Kit

EK-059-02 96 wells
EUR 617.76

Peptide YY (PYY) (3-36) (Human) - RIA Kit

RK-059-02 125 tubes
EUR 814.32

Peptide YY (PYY) (Human) - I-125 Labeled

T-059-01 10 μCi
EUR 1145.88

SHLP1 / Small Humanin-Like Peptide 1 (Human)

018-75 100 μg
EUR 263.52

SHLP2 / Small Humanin-Like Peptide 2 (Human)

018-76 100 μg
EUR 263.52

SHLP3 / Small Humanin-Like Peptide 3 (Human)

018-77 100 μg
EUR 422.28

SHLP4 / Small Humanin-Like Peptide 4 (Human)

018-78 100 μg
EUR 289.44

SHLP5 / Small Humanin-Like Peptide 5 (Human)

018-79 100 μg
EUR 316.44

SHLP6 / Small Humanin-Like Peptide 6 (Human)

018-80 100 μg
EUR 250.56

Gastrin Releasing Peptide (GRP) (Human) - Purified IgG Antibody

G-027-07 400 μg
EUR 438.48

Agouti-Related Peptide (AgRP) (83-132) amide (Human) - Antibody

H-003-53 50 μl
EUR 469.8

Galanin-Like Peptide (GALP) (36-60) (Human)

026-55 200 μg
EUR 177.12

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - RIA Kit

RK-064-07 125 tubes
EUR 932.04

FGF23 (188-199 )optimized peptide 10 (Human)

073-88 100 μg
EUR 258.12

Stresscopin Related Peptide (SRP) (Human) - Purified IgG Antibody

G-019-27 200 μg
EUR 604.8

Prolactin-Releasing Peptide-31 (PrRP-31) (Human)

008-50 200 μg
EUR 199.8

Prolactin-Releasing Peptide-20 (PrRP-20) (Human)

008-51 200 μg
EUR 199.8

Peptide YY (PYY) (3-36) (Human) - FAM Labeled

FG-059-02A 1 nmol
EUR 336.96

Agouti-Related Peptide (AgRP) (25-51) (Human)

003-51 200 μg
EUR 129.6

Agouti-Related Peptide (AgRP) (54-82) (Human)

003-52 200 μg
EUR 129.6

Agouti-Related Peptide (AgRP) (25-82) (Human)

003-74 100 μg
EUR 497.88

Gastrin Releasing Peptide (GRP) (18-27) (Human)

027-41 200 μg
EUR 160.92

Seminal Plasma Inhibin-Like Peptide (Human)

034-03 200 μg
EUR 194.4

Gastrin Releasing Peptide (GRP) (1-16) (Human)

027-08 1 mg
EUR 177.12

Gastrin Releasing Peptide (GRP) (1-17) (Human)

027-42 200 μg
EUR 189

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - FAM Labeled

FG-064-07A 1 nmol
EUR 336.96

Galanin-Like Peptide (GALP) (Human) - RIA Kit

RK-026-51 125 tubes
EUR 932.04

Prolactin-Releasing Peptide-31 (PrRP-31) (Human) - Purified IgG Antibody

G-008-50 400 μg
EUR 604.8

Galanin-Like Peptide (GALP) (36-60) (Human) - Purified IgG Antibody

G-026-55 200 μg
EUR 604.8

[Tyr0]-pro-Gastrin Releasing Peptide (GRP) (80-97) (Human) - Antibody

H-027-36 100 μl
EUR 370.44

Peptide YY (PYY) (3-36) (Human) - Biotin Labeled

B-059-02 10 μg
EUR 405

RFamide-Related Peptide 1 (RFRP-1) (Human)

048-42 500 μg
EUR 177.12

RFamide-Related Peptide 2 (RFRP-2) (Human)

048-44 500 μg
EUR 177.12

RFamide-Related Peptide 3 (RFRP-3) (Human)

048-46 500 μg
EUR 177.12

Gastrin Releasing Peptide (GRP) (Human) - EIA Kit

EK-027-07 96 wells
EUR 603.72

Gastrin Releasing Peptide (GRP) (Human) - RIA Kit

RK-027-07 125 tubes
EUR 932.04

Urotensin II Related Peptide (Human, Rat, Mouse)

071-17 200 μg
EUR 129.6

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - I-125 Labeled

T-064-07 10 μCi
EUR 1145.88

T3 Peptide / Tumstatin (69-88) (Human) - FAM Labeled

FG-016-50A 1 nmol
EUR 469.8

T7 Peptide / Tumstatin (74-98) (Human) - FAM Labeled

FG-016-51A 1 nmol
EUR 469.8

Galanin-Like Peptide (GALP) (Human) - FAM Labeled

FG-026-51A 1 nmol
EUR 604.8

Stresscopin Related Peptide (SRP) (Human) - RIA Kit

RK-019-27 125 tubes
EUR 1341.36

Peptide YY (PYY) (3-36) (Human) - I-125 Labeled

T-059-02 10 μCi
EUR 1145.88

Peptide YY (PYY) (3-36) (Human) - Rhodamine Labeled

FR-059-02 1 nmol
EUR 405

Peptide YY (PYY) (3-36) (Human) - MagBead (Magnetic Bead Linked Antibody)

MB-059-02 1 ml
EUR 842.4

Gastrin Releasing Peptide-Gly (GRP-Gly) (Human)

027-37 100 μg
EUR 160.92

[Tyr0]-Agouti-Related Peptide (AgRP) (25-51) (Human)

003-72 100 μg
EUR 416.88

[Tyr0]-Agouti-Related Peptide (AgRP) (54-82) (Human)

003-73 100 μg
EUR 416.88

prepro-RFamide Related Peptide (RFRP) (56-92) amide (Human) - Antibody

H-048-54 100 μl
EUR 604.8

prepro-RFamide Related Peptide (RFRP) (115-131) amide (Human) - Antibody

H-048-55 50 μl
EUR 604.8

R3 (BDelta23-27) R / I5 Chimeric Peptide (Human)

035-66 100 μg
EUR 604.8

Nesfatin-1-Like Peptide(NLP) (Human) - RIA Kit

RK-009-83 125 tubes
EUR 980.64

7B2 Carboxyl-terminal (CT) peptide (Human, Porcine)

004-32 100 μg
EUR 160.92

Osteoblast Activating Peptide (OBAP) (Human) - EIA Kit

EK-055-52 96 wells
EUR 660.96

Osteoblast Activating Peptide (OBAP) (Human) - RIA Kit

RK-055-52 125 tubes
EUR 980.64

pro-Gastrin Releasing Peptide (GRP) (42-98) (Human)

027-34 100 μg
EUR 355.32

pro-Gastrin Releasing Peptide (GRP) (47-68) (Human)

027-35 100 μg
EUR 160.92

SHAAG Peptide / Chemokine (46-63) (Human) - Cy3 Labeled

FC3-072-32 1 nmol
EUR 587.52

SHAAG Peptide / Chemokine (46-63) (Human) - Cy5 Labeled

FC5-072-32 1 nmol
EUR 587.52

SHAAG Peptide / Chemokine (46-63) (Human) - FAM Labeled

FG-072-32A 1 nmol
EUR 267.84

Agouti-Related Peptide (AgRP) (71-132), Form C amide (Human) - Antibody

H-003-55 50 μl
EUR 604.8

Stresscopin Related Peptide (SRP) (Human) - FAM Labeled

FG-019-27A 1 nmol
EUR 537.84

prepro-Galanin-Like Peptide (GALP) (87-116) (Human)

026-54 200 μg
EUR 230.04

Urotensin II Related Peptide (Human, Rat, Mouse) - Purified IgG Antibody

G-071-17 200 μg
EUR 604.8

Peptide YY (PYY) (3-36) (Human) - Fluorescent EIA Kit

FEK-059-02 96 wells
EUR 660.96

Agouti-Related Peptide (AgRP) (83-132) amide (Human)

003-53 100 μg
EUR 316.44

[Leu(13C)6,(15N)-15,22]-Peptide YY (PYY) (3-36) (Human)

SIL-059-02 20 μg
EUR 1186.92

Gastrin Releasing Peptide (GRP) (14-27) (Human, Porcine)

027-16 500 μg
EUR 108

Prostate Specific Antigen (PSA) (243-261) / C-terminal PSA peptide (Human)

034-45 100 μg
EUR 199.8

[Tyr0]-RFamide-Related Peptide 1 (RFRP-1) (Human)

048-43 200 μg
EUR 177.12

[Tyr0]-RFamide-Related Peptide 2 (RFRP-2) (Human)

048-45 200 μg
EUR 177.12

[Tyr0]-RFamide-Related Peptide 3 (RFRP-3) (Human)

048-47 200 μg
EUR 177.12

Galanin-Like Peptide (GALP) (Human) - Rhodamine Labeled

FR-026-51 1 nmol
EUR 604.8

Parathyroid Hormone-Like Peptide (PLP) (140-173) (Human)

056-17 200 μg
EUR 129.6

SHAAG Peptide / Chemokine (46-63) (Human) - Biotin Labeled

B-072-32 10 μg
EUR 267.84

Prolactin-Releasing Peptide-31 (PrRP-31) (Human) - EIA Kit

EK-008-50 96 wells
EUR 603.72

Prolactin-Releasing Peptide-31 (PrRP-31) (Human) - RIA Kit

RK-008-50 125 tubes
EUR 932.04

Galanin-Like Peptide (GALP) (Human) - I-125 Labeled

T-026-51 10 μCi
EUR 1145.88

Osteoblast Activating Peptide (OBAP) (Human) - Cy3 Labeled

FC3-055-52 1 nmol
EUR 756

Osteoblast Activating Peptide (OBAP) (Human) - Cy5 Labeled

FC5-055-52 1 nmol
EUR 756

Osteoblast Activating Peptide (OBAP) (Human) - FAM Labeled

FG-055-52 1 nmol
EUR 537.84

Galanin-Like Peptide (GALP) (Human) - Western Blot Kit

WBK-026-51 1 kit
EUR 822.96

Peptide YY (PYY) (3-36) (Human) - Magnetic Bead RIA Kit

MRK-059-02 125 tubes
EUR 1061.64

Agouti-Related Peptide (AgRP) (83-132) amide (Human) - Purified IgG Antibody

G-003-53 400 μg
EUR 604.8

Gastrin Releasing Peptide (GRP) (Human) - I-125 Labeled

T-027-07 10 μCi
EUR 1145.88

SHAAG Peptide / Chemokine (46-63) (Human) - Rhodamine Labeled

FR-072-32 1 nmol
EUR 336.96

Peptide YY (PYY) (Human) - I-125 Labeled Purified IgG

T-G-059-01 10 μCi
EUR 1145.88

Galanin-Like Peptide (GALP) (36-60) (Human) - FAM Labeled

FG-026-55A 1 nmol
EUR 604.8

SHAAG Peptide / Chemokine (46-63) (Human) - I-125 Labeled

T-072-32 10 μCi
EUR 1145.88

prepro-Endothelin-1 (ET-1) Like Peptide (109-130) amide (Human)

023-11 100 μg
EUR 355.32

Peptide YY (PYY) (3-36) (Human) - Chemiluminescent EIA Kit

CEK-059-02 96 wells
EUR 660.96

Peptide Histidine Methionine 27 (PHM-27) / Peptide Histidine Isoleucine (PHI) (Human) - I-125 Labeled Purified IgG

T-G-064-07 10 μCi
EUR 1145.88

Osteoblast Activating Peptide (OBAP) (Human) - Biotin Labeled

B-055-52 100 μg
EUR 469.8

Stresscopin Related Peptide (SRP) (Human) - Rhodamine Labeled

FR-019-27 1 nmol
EUR 537.84

Prolactin-Releasing Peptide-31 (PrRP-31) (Human) - FAM Labeled

FG-008-50A 1 nmol
EUR 336.96

Prolactin-Releasing Peptide-20 (PrRP-20) (Human) - FAM Labeled

FG-008-51A 1 nmol
EUR 336.96

Self-Immobilized Putrescine Oxidase Biocatalyst System Engineered with a Steel Binding Peptide

Flavin oxidases are useful biocatalysts for the oxidative synthesis of a big selection of compounds, whereas on the similar time lowering oxygen to hydrogen peroxide. In comparison with different redox enzymes, their means to make use of molecular oxygen as an electron acceptor presents a comparatively easy system which doesn’t require a dissociable coenzyme. As such, they’re enticing targets for adaptation as value efficient biosensor components. Their useful immobilization on surfaces presents distinctive alternatives to broaden their utilization for a variety of purposes. Genetically engineered peptides have been demonstrated as enablers of the useful meeting of biomolecules at stable supplies interfaces.

As soon as recognized as having a excessive affinity for the fabric of curiosity, these peptides can present a single step bio-assembly course of with orientation management, a important parameter for useful immobilization of the enzymes. On this research, for the primary time, we explored bio-assembly of a putrescine oxidase enzyme utilizing a gold binding peptide tag.

 The enzyme was genetically engineered to include a gold binding peptide with an expectation of efficient show of the peptide tag to work together with the gold floor. On this work, the useful exercise and expression have been investigated, together with the selectivity of the binding of the peptide tagged enzyme. The fusion enzyme was characterised utilizing a number of strategies together with protein electrophoresis, enzyme exercise, microscopic and spectroscopic strategies to confirm useful expression of the tagged protein with close to native exercise.

Binding research utilizing quartz crystal microbalance (QCM), nanoparticle binding research, and atomic power microscopy research have been used to handle the selectivity of the binding by way of the peptide tag. Floor binding AFM research present that the binding was selective for gold. Quartz crystal microbalance research present a powerful improve within the affinity of the peptide tagged protein over the native enzyme, whereas exercise assays of protein certain to nanoparticles present proof that the enzyme retained catalytic exercise when immobilized.

 Along with displaying selectivity, AFM pictures present vital variations within the top of the molecules when immobilized by way of the peptide tag in comparison with immobilization of the native enzyme, indicating variations in orientation of the certain enzyme when connected through the affinity tag. Controlling orientation of floor immobilized enzymes would additional enhance their enzymatic exercise and affect various purposes together with oxidative biocatalysis, biosensors, biochips, and biofuel manufacturing.

VEGFR-KDR/Flk-1 Antagonist Peptide

H-5896.0005 5.0mg
EUR 2648.4
Description: Sum Formula: C77H99N23O18S; CAS# [492444-99-2] net

VEGFR binding peptide KH / QKRKRKKSRKKH

007-58 100 μg
EUR 158.76

VEGFR binding peptide IVLS / RKRKRKKSRYIVLS

007-59 100 μg
EUR 171.72

Rat Anti-Mouse VEGFR-2/Flk-1

MBS690969-005mg 0.05mg
EUR 430

Rat Anti-Mouse VEGFR-2/Flk-1

MBS690969-5x005mg 5x0.05mg
EUR 1645

Anti-Mouse VEGFR-2/Flk-1 Antibody

103-M32 100 µg
EUR 189
Description: VEGF R2 (mouseFlk1 gene), VEGF R1 (Flt1) and VEGF R3 (Flt4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulinlike repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mouse VEGF R2 cDNA encodes a 1367 amino acid (aa) precursor protein with a 19 aa signal peptide. Mature VEGF R2 is composed of a 743 aa extracellular domain, a 22 aa transmembrane domain, and a 583 aa cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The solube receptor was used as a an antigen.

Anti-Mouse VEGFR-2/FLK-1 Antibody

103-M35 100 µg
EUR 399
Description: VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Anti-Mouse VEGFR-2/FLK-1 Antibody

103-M35A 100 µg
EUR 399
Description: VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Anti-Mouse VEGFR-2/Flk-1 Antibody

103-MBi32 50 µg
EUR 189
Description: VEGF R2 (mouseFlk1 gene), VEGF R1 (Flt1) and VEGF R3 (Flt4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulinlike repeats in their extracellular domains and kinase insert domains in their intracellular regions. The expression of VEGF R1, 2, and 3 is almost exclusively restricted to the endothelial cells. These receptors are likely to play essential roles in vasculogenesis and angiogenesis. Mouse VEGF R2 cDNA encodes a 1367 amino acid (aa) precursor protein with a 19 aa signal peptide. Mature VEGF R2 is composed of a 743 aa extracellular domain, a 22 aa transmembrane domain, and a 583 aa cytoplasmic domain. In contrast to VEGF R1 which binds both PlGF and VEGF with high affinity, VEGF R2 binds VEGF but not PlGF with high affinity. The solube receptor was used as a an antigen.

Anti-Mouse VEGFR-2/Flk-1 Antibody

103-PA18S 100 µg
EUR 126
Description: The antibody recognizes mouse vascular endothelial growth factor receptor 2, alos known as CD309, VEGFR2, KDR, protein tyrosine kinase receptor flk-1, and fetal liver kinase-1. Flk-1 is a member of the tyrosine protein kinase family, sub-family CSF-1/PDGF, that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. Flk-1 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle; other tissues express at lower levels. Flk-1 is a receptor for VEGF-A or fully processed VEGF-C; ligand binding plays a key role in vascular development and vascular permeability.

Mouse VEGFR-2/Flk-1 (native), soluble

MBS691679-0005mg 0.005mg
EUR 340

Mouse VEGFR-2/Flk-1 (native), soluble

MBS691679-5x0005mg 5x0.005mg
EUR 1245

Mouse VEGFR-2/Flk-1 (native), soluble

MBS691714-002mg 0.02mg
EUR 565

Mouse VEGFR-2/Flk-1 (native), soluble

MBS691714-5x002mg 5x0.02mg
EUR 2245

Rabbit Anti-Mouse VEGFR-2 Flk-1, soluble

103-PA18 100ug
EUR 240

Mouse VEGFR-2/Flk-1 (native), soluble Recombinant Protein

S01-M03 5 µg
EUR 126
Description: Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vessel growth has not to our knowledge been previously described. A splice variant of the gene encoding vascular endothelial growth factor receptor-2 (VEGFR-2) that encodes a secreted form of the protein, designated endogenous soluble VEGFR-2 (esVEGFR-2/KDR) has been described. The endogenous soluble esKDR inhibits developmental and reparative lymphangiogenesis by blocking VEGF-C function. Tissue-specific loss of esKDR in mice induced, at birth, spontaneous lymphatic invasion of the normally alymphatic cornea and hyperplasia of skin lymphatics without affecting blood vasculature. Administration of esKDR inhibited lymphangiogenesis but not hemangiogenesis induced by corneal suture injury or transplantation, enhanced corneal allograft survival and suppressed lymphangioma cellular proliferation. Naturally occurring esKDR thus acts as a molecular uncoupler of blood and lymphatic vessels; modulation of esKDR might have therapeutic effects in treating lymphatic vascular malformations, transplantation rejection and, potentially, tumor lymphangiogenesis and lymphedema. Recombinant human esKDR generated by alternative splicing consist of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP.

Mouse VEGFR-2/Flk-1 (native), soluble Recombinant Protein

S01-M04 20 µg
EUR 273
Description: Disruption of the precise balance of positive and negative molecular regulators of blood and lymphatic vessel growth can lead to myriad diseases. Although dozens of natural inhibitors of hemangiogenesis have been identified, an endogenous selective inhibitor of lymphatic vessel growth has not to our knowledge been previously described. A splice variant of the gene encoding vascular endothelial growth factor receptor-2 (VEGFR-2) that encodes a secreted form of the protein, designated endogenous soluble VEGFR-2 (esVEGFR-2/KDR) has been described. The endogenous soluble esKDR inhibits developmental and reparative lymphangiogenesis by blocking VEGF-C function. Tissue-specific loss of esKDR in mice induced, at birth, spontaneous lymphatic invasion of the normally alymphatic cornea and hyperplasia of skin lymphatics without affecting blood vasculature. Administration of esKDR inhibited lymphangiogenesis but not hemangiogenesis induced by corneal suture injury or transplantation, enhanced corneal allograft survival and suppressed lymphangioma cellular proliferation. Naturally occurring esKDR thus acts as a molecular uncoupler of blood and lymphatic vessels; modulation of esKDR might have therapeutic effects in treating lymphatic vascular malformations, transplantation rejection and, potentially, tumor lymphangiogenesis and lymphedema. Recombinant human esKDR generated by alternative splicing consist of the first 6 Ig-like loops followed by the unique C-terminal end: GMEASLGDRIAMP.

Rabbit Anti-Mouse FLK-1/VEGFR-2 IgG #1, aff pure

FLK11-A 100 ug
EUR 578.4

Mouse FLT-4/VEGFR-3 Control/blocking peptide #1

FLT41-P 100 ug
EUR 196.8

Anti-Human VEGFR-2/KDR (Peptide), soluble Antibody

102-PA19S 100 µg
EUR 126
Description: VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. Human VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

Rabbit Anti-Human VEGFR-2/KDR (Peptide), soluble

102-PA19 100ug
EUR 240

Anti-Human VEGFR-1/Flt-1 (Peptide), soluble Antibody

102-PA21S 100 µg
EUR 126
Description: Endothelial cells express three different vascular endothelial growth factor (VEGF) receptors, belonging to the family of receptor tyrosine kinases (RTKs). They are named VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1), VEGFR-3 (Flt-4). Their expression is almost exclusively restricted to endothelial cells, but VEGFR-1 can also be found on monocytes, dendritic cells and on trophoblast cells. The flt-1 gene was first described in 1990. The receptor contains seven immunoglobulin-like extracellular domains, a single transmembrane region and an intracellular splited tyrosine kinase domain. Compared to VEGFR-2 the Flt-1 receptor has a higher affinity for VEGF but a weaker signaling activity. VEGFR-1 thus leads not to proliferation of endothelial cells, but mediates signals for differentiation. Interestingly a naturally occuring soluble variant of VEGFR-1 (sVEGFR-1) was found in HUVEC supernatants in 1996, which is generated by alternative splicing of the flt-1 mRNA.

Rabbit Anti-Human VEGFR-1 Flt-1 (Peptide), soluble

102-PA21 100ug
EUR 240

Biotinylated-Mouse Monoclonal Anti-Human FLK-1/VEGFR-2 IgG # 3

FLK13-MB 100 ug
EUR 489.6

CD309 / VEGFR-2 / Flk-1 rabbit polyclonal antibody

RA25011-100 100 µl Ask for price

Anti-Inflammatory Peptide 2

004-02 200 μg
EUR 27

Nesfatin-1-Like Peptide (NLP) (Mouse)

009-81 100 μg
EUR 469.8

Peptide Lv (Mouse)

008-72 100 μg
EUR 469.8

Anti-Inflammatory Peptide 1

004-01 200 μg
EUR 27

RFamide-Related Peptide 1 (RFRP-1) (Rat, Mouse)

048-48 500 μg
EUR 177.12

Laminin A-Chain Peptide / PA22-2 (Rat, Mouse)

038-07 500 μg
EUR 135

[Tyr0]-RFamide-Related Peptide 1 (RFRP-1) (Rat, Mouse)

048-49 200 μg
EUR 177.12

Gastrin Releasing Peptide (GRP) (1-19) (Rat, Mouse)

027-44 200 μg
EUR 189

Nesfatin-1-Like Peptide (NLP) (Mouse) - RIA Kit

RK-009-81 125 tubes
EUR 980.64

Peptide YY (PYY) (1-36)-Gly (Rat, Mouse, Porcine, Canine) - Antibody

H-059-06 100 μl
EUR 336.96

CD309 / VEGFR-2 / Flk-1 rabbit polyclonal antibody, Purified

AP26035PU-L 200 µg Ask for price

CD309 / VEGFR-2 / Flk-1 rabbit polyclonal antibody, Purified

AP33406PU-L 200 µg Ask for price

CD309 / VEGFR-2 / Flk-1 rabbit polyclonal antibody, Purified

AP33406PU-N 100 µg Ask for price

Peptide YY (PYY) (2-36)-Gly (Rat, Mouse, Porcine, Canine)

059-10 100 μg
EUR 267.84

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 Elisa kit

EK730360 96 Wells
EUR 0.68

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 Elisa kit

EK731156 96 Wells
EUR 0.75

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit

EKC38030-48T 48T
EUR 474.04

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit

EKC38030-5x96T 5x96T
EUR 3216.7

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA kit

EKC38030-96T 96T
EUR 677.2

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

EK10234 96Т
EUR 799

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

AE37011MO-48Tests 48 Tests
EUR 325
Description: Mouse (Mus musculus)

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

AE37011MO-96Tests 96 Tests
EUR 610
Description: Mouse (Mus musculus)

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA kit

CSB-E04764m-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 in samples from serum, plasma. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA kit

1-CSB-E04764m
  • Ask for price
  • Ask for price
  • Ask for price
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 in samples from serum, plasma. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Mouse Vascuoar endothelial cell growth factor receptor 2,(VEGFR-2/Flk-1)ELISA Kit

YLA0973MO-48T 48T Ask for price

Mouse Vascuoar endothelial cell growth factor receptor 2,(VEGFR-2/Flk-1)ELISA Kit

YLA0973MO-96T 96T Ask for price

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E2557Mo-1096T 10*96T
EUR 4122

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E2557Mo-48wells 48 wells
EUR 300

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E2557Mo-596T 5*96T
EUR 2061

Mouse Vascular endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E2557Mo-96wells 96 wells
EUR 458

Mouse Vascuoar endothelial cell growth factor receptor 2((VEGFR-2/Flk-1)ELISA Kit

GA-E0681MS-48Tests 48 Tests Ask for price

Mouse Vascuoar endothelial cell growth factor receptor 2((VEGFR-2/Flk-1)ELISA Kit

GA-E0681MS-96Tests 96 Tests
EUR 460

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E0668Mo-1096T 10*96T
EUR 4122

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E0668Mo-48wells 48 wells
EUR 300

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E0668Mo-596T 5*96T
EUR 2061

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2;Flk-1 ELISA KIT

E0668Mo-96wells 96 wells
EUR 458

Mouse Vascuoar endothelial cell growth factor receptor 2((VEGFR-2/Flk-1)ELISA Kit

GA-E0681MS-48T 48T
EUR 403.2

Mouse Vascuoar endothelial cell growth factor receptor 2((VEGFR-2/Flk-1)ELISA Kit

GA-E0681MS-96T 96T
EUR 640.8

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

RK00153 96T
EUR 280

Mouse Vascuoar endothelial cell growth factor receptor 2,VEGFR-2/Flk-1 ELISA Kit

SL0561Mo -
EUR 528

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

AE37011MO-48T 48T
EUR 325
Description: Mouse (Mus musculus)

Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) ELISA Kit

AE37011MO-96T 96T
EUR 610
Description: Mouse (Mus musculus)

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS702919-10x96StripWells 10x96-Strip-Wells
EUR 5325

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS702919-24StripWellsLIMIT1 24-Strip-Wells(LIMIT1)
EUR 275

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS702919-48StripWells 48-Strip-Wells
EUR 480

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS702919-5x96StripWells 5x96-Strip-Wells
EUR 2795

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS702919-96StripWells 96-Strip-Wells
EUR 675

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS9302041-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS9302041-48StripWells 48-Strip-Wells
EUR 550

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS9302041-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS9302041-96StripWells 96-Strip-Wells
EUR 765

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS162389-10x96StripWells 10x96-Strip-Wells
EUR 3955

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS162389-48StripWells 48-Strip-Wells
EUR 305

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS162389-5x96StripWells 5x96-Strip-Wells
EUR 2005

Mouse Vascuoar endothelial cell growth factor receptor 2, (VEGFR-2/Flk-1) ELISA Kit

MBS162389-96StripWells 96-Strip-Wells
EUR 475

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS1605761-10x96StripWells 10x96-Strip-Wells
EUR 3955

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS1605761-48StripWells 48-Strip-Wells
EUR 305

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS1605761-5x96StripWells 5x96-Strip-Wells
EUR 2005

Mouse Vascular endothelial cell growth factor receptor 2, VEGFR-2/Flk-1 ELISA Kit

MBS1605761-96StripWells 96-Strip-Wells
EUR 475

Mouse Vascuoar endothelial cell Growth Factor Receptor 2, VEGFR-2/Flk-1 GENLISA ELISA

KLM0668 1 x 96 wells
EUR 341

Mouse Vascular endothelial cell Growth Factor Receptor 2, VEGFR-2/Flk-1 GENLISA ELISA

KLM2557 1 x 96 wells
EUR 341

Peptide YY (PYY) (1-36)-Gly (Rat, Mouse, Porcine, Canine)

059-06 100 μg
EUR 282.96

Bone Forming Peptide 1 (BFP-1) (Human, Rat, Mouse, Bovine, Feline)

080-57 100ug
EUR 196.56

Gastrin Releasing Peptide (GRP) (Mouse)

027-40 100 μg
EUR 160.92

Peptide YY (PYY) (Rat, Mouse, Porcine, Canine) - Antibody

H-059-03 100 μl
EUR 469.8

Recombinant Human KDR/VEGFR-2/FLK-1(C-6His)

CB26-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human KDR/VEGFR-2/FLK-1(C-6His)

CB26-1mg 1mg
EUR 2983.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human KDR/VEGFR-2/FLK-1(C-6His)

CB26-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

Recombinant Human KDR/VEGFR-2/FLK-1(C-6His)

CB26-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.

ELISA kit for Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1)

KTE71214-48T 48T
EUR 398.4
Description: Quantitative sandwich ELISA for measuring Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1)

KTE71214-5platesof96wells 5 plates of 96 wells
EUR 2538
Description: Quantitative sandwich ELISA for measuring Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

ELISA kit for Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1)

KTE71214-96T 96T
EUR 646.8
Description: Quantitative sandwich ELISA for measuring Mouse Vascular endothelial cell growth factor receptor 2 (VEGFR-2/Flk-1) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.

Urotensin II Related Peptide (Human, Rat, Mouse) - Antibody

H-071-17 50 μl
EUR 604.8

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